Recombinant Prohibitin Monoclonal Antibody

Recombinant Prohibitin Monoclonal Antibody

• Background: Prohibitin,also known as PHB,a member of the Band-7 family of proteins,is widely distributed in bacteria,plants,yeast,protozoa and mammals and is important in cell proliferation,differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria,where it acts as a chaperone protein,and is also found in the nucleus,where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB,which is a nuclear matrix protein,affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
• Synonyms: Epididymis luminal protein 215,Epididymis secretory sperm binding protein Li 54e,HEL 215,HEL S 54e,PHB,PHB,PHB1,Prohibitin
• Gene ID: 5245
• Swiss Prot: P35232
• Host: Rabbit
• Reactivity: Human,Rat
• Immunogen: A synthetic peptide of human Prohibitin
• Clonality: Monoclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB,IHC-P
• Purification: Affinity purification
• Concentration: 300 μg/mL
• Dilution: WB 1:500-1:1000, IHC 1:50-1:100
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
• Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 57 kDa
• Observed Molecular Weight: 57 kDa