DSG1 Polyclonal Antibody
CAT:
866-RD86891A-01
Size:
60 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DSG1 Polyclonal Antibody
- Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
- Synonyms: DSG1,CDHF4,DG1,DSG,EPKHE,EPKHIA,PPKS1,SPPK1
- Gene ID: 1828
- Swiss Prot: Q02413
- Host: Rabbit
- Reactivity: Human,Rat
- Immunogen: Recombinant fusion protein of human DSG1
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB,IF
- Purification: Affinity purification
- Concentration: 1 mg/mL
- Dilution: WB 1:500-1:2000,IF 1:50-1:100
- Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
- Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- Calculated Molecular Weight: 44kDa/57kDa
- Observed Molecular Weight: 38-45KDa