Recombinant mtTFA Monoclonal Antibody

Recombinant mtTFA Monoclonal Antibody

• Background: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.
• Synonyms: anscription factor 6-like 1,Mitochondrial transcription factor 1,mitochondrial transcription factor A,MtTF1,mtTFA,TCF 6,TCF-6,TCF6,TCF6L1,TCF6L2,TCF6L3,TFAM,TFAM,Transcription factor 6,Transcription factor 6 like 2 (mitochondrial transcription factor),Transcription factor 6 like 2,Transcription factor 6-like 2,transcription factor 6-like 3,Transcription factor A,mitochondrial,Transcription factor A,mitochondrial,Transcription factor A,mitochondrial precursor
• Gene ID: 7019
• Swiss Prot: Q00059
• Host: Rabbit
• Reactivity: Human
• Immunogen: A synthetic peptide of human mtTFA
• Clonality: Monoclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB,IHC-P,IF
• Purification: Affinity purification
• Concentration: 300 μg/mL
• Dilution: WB 1:1000-1:2000, IHC 1:50-1:100, IF 1:50-1:100
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
• Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 149kDa
• Observed Molecular Weight: 115kDa