Phospho-HDAC6 (Ser22) Polyclonal Antibody

Phospho-HDAC6 (Ser22) Polyclonal Antibody

• Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
• Synonyms: CPBHM,FLJ16239,HD 6,HD6,HDAC 6,HDAC6,HDAC6,Histone deacetylase 6 (HD6),Histone deacetylase 6,JM 21,JM21,KIAA0901,OTTHUMP00000032398,OTTHUMP00000197663,PPP1R90,Protein phosphatase 1 regulatory subunit 90
• CAS Number: 9007-83-4
• Swiss Prot: Q9UBN7
• Host: Rabbit
• Reactivity: Human,Mouse
• Immunogen: Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22
• Clonality: Polyclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB,IHC-p,IF,ELISA
• Purification: Affinity purification
• Concentration: 1 mg/mL
• Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
• Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 131 kDa
• Observed Molecular Weight: 131 kDa