CHD3 Polyclonal Antibody
CAT:
866-RD82608A-01
Size:
60 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CHD3 Polyclonal Antibody
- Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
- Synonyms: CHD3,Mi-2a,Mi2-ALPHA,ZFH
- CAS Number: 9007-83-4
- Gene ID: 1107
- Swiss Prot: Q12873
- Host: Rabbit
- Reactivity: Human,Mouse,Rat
- Immunogen: A synthetic peptide of human CHD3 (NP_001005273.1).
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB
- Purification: Affinity purification
- Concentration: 1 mg/mL
- Dilution: WB 1:200-1:1000
- Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
- Calculated Molecular Weight: 222 kDa/226 kDa/233 kDa
- Observed Molecular Weight: 280 kDa