AF647 Anti-Human CD16 Antibody
CAT:
866-RD30456F-03
Size:
2x 100 Tests
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AF647 Anti-Human CD16 Antibody
- Background: CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
- Synonyms: FcγRIII,Fc gamma receptor,Fc gamma receptor 3
- CAS Number: 9007-83-4
- Gene ID: 941
- Swiss Prot: P08637,O75015
- Host: Mouse
- Reactivity: Human
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Conjugation: AF647
- Applications: FCM
- Buffer: PBS with 0.05% Proclin300, 1% BSA
- Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.