AF488 Anti-Human CD39 Antibody

AF488 Anti-Human CD39 Antibody

• Background: Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details
• Synonyms: SPG64,NTPDase1,ATPDase,CD 39
• CAS Number: 9007-83-4
• Gene ID: 953
• Swiss Prot: P49961
• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Conjugation: AF488
• Applications: FCM
• Buffer: PBS with 0.05% Proclin300, 1% BSA
• Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.