FBXW8 Polyclonal Antibody

FBXW8 Polyclonal Antibody

• Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
• Synonyms: F box and WD40 domain containing protein 8,F box only protein 29,F box/WD repeat containing protein 8,F-box and WD-40 domain-containing protein 8,F-box only protein 29,F-box/WD repeat-containing protein 8,FBW6,FBW8,FBX29,FBXO29,FBXW6,FBXW8,FBXW8
• CAS Number: 9007-83-4
• Swiss Prot: Q8N3Y1
• Accession Number: NP699179
• Host: Rabbit
• Reactivity: Human
• Immunogen: Synthetic peptide of human FBXW8
• Clonality: Polyclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: IHC,ELISA
• Purification: Antigen affinity purification
• Concentration: 1.92 mg/mL
• Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000
• Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.