PerCP/Cyanine5.5 Anti-Human CD45 Antibody
CAT:
866-RD21704F-01
Size:
20 Tests
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PerCP/Cyanine5.5 Anti-Human CD45 Antibody
- Background: CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
- Synonyms: Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
- CAS Number: 9007-83-4
- Gene ID: 5788
- Swiss Prot: P08575
- Host: Mouse
- Reactivity: Human
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Conjugation: PerCP/Cyanine5.5
- Applications: FCM
- Buffer: PBS with 0.05% Proclin300, 1% BSA
- Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.