AF488 Anti-Human CD62L Antibody
CAT:
866-RD20710F-02
Size:
100 Tests
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AF488 Anti-Human CD62L Antibody
- Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
- Synonyms: L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22
- CAS Number: 9007-83-4
- Gene ID: 6402
- Swiss Prot: P14151
- Host: Mouse
- Reactivity: Human
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Conjugation: AF488
- Applications: FCM
- Buffer: PBS with 0.05% Proclin300, 1% BSA
- Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.