PE Anti-Mouse CD40 Antibody

PE Anti-Mouse CD40 Antibody

• Background: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
• Synonyms: Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
• CAS Number: 9007-83-4
• Gene ID: 21939
• Swiss Prot: P27512
• Host: Rat
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Conjugation: PE
• Applications: FCM
• Buffer: PBS with 0.05% Proclin300, 1% BSA
• Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.