Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody, Carrier-free

Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody, Carrier-free

• Description: Boster Bio Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody catalog # M01332. Tested in WB application. This antibody reacts with Human, Mouse, Rat.
• Synonyms: Nuclear receptor subfamily 5 group A member 2;Alpha-1-fetoprotein transcription factor;B1-binding factor;hB1F;CYP7A promoter-binding factor;Hepatocytic transcription factor;Liver receptor homolog 1;LRH-1;NR5A2;B1F, CPF, FTF;
• Gene Name: Nuclear receptor subfamily 5 group A member 2
• UniProt: O00482
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthesized peptide derived from human NR5A2
• Clonality: Monoclonal
• Clone: Clone: ABHO-14
• Tissue Specificity: Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells.
• Applications: WB
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
• Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
• Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 61331 MW
• Observed Molecular Weight: 105 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:500-1:2000
• Subcellular Location: Nucleus .
• Protein Name: Glycogen synthase kinase-3 beta (gsk3b)