Lentinan
CAT:
804-HY-N6653
Size:
100 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Lentinan
- CAS Number: 37339-90-5
- UNSPSC Description: Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering[1][4].
- Target Antigen: Apoptosis; JAK; Keap1-Nrf2
- Type: Natural Products
- Related Pathways: Apoptosis;Epigenetics;JAK/STAT Signaling;NF-κB;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-programmed cell death
- Field of Research: Cancer; Infection; Metabolic Disease; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/lentinan.html
- Solubility: 0.1 M NaOH : 33.33 mg/mL (ultrasonic;adjust pH to 9 with NaOH)|Acetone : < 1 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
- Smiles: [Lentinan]
- References & Citations: [1]Meng M, et al. Lentinan inhibits oxidative stress and alleviates LPS-induced inflammation and apoptosis of BMECs by activating the Nrf2 signaling pathway. Int J Biol Macromol. 2022 Dec 1;222(Pt B):2375-2391. |[2]Cui H, et al. Anti-Influenza Effect and Mechanisms of Lentinan in an ICR Mouse Model. Front Cell Infect Microbiol. 2022 May 20;12:892864. |[3]Wang SX, et al. Lentinan ameliorates burn sepsis by attenuating CD4+ CD25+ Tregs. Burns. 2016 Nov;42(7):1513-1521. |[4]Chen Q, et al. Upregulation of miR-216a-5p by Lentinan Targeted Inhibition of JAK2/STAT3 Signaling Pathway to Reduce Lung Adenocarcinoma Cell Stemness, Promote Apoptosis, and Slow Down the Lung Adenocarcinoma Mechanisms. Front Oncol. 2021 Nov 25;11:778096. |[5]Ji X, et al. Lentinan improves intestinal inflammation and gut dysbiosis in antibiotics-induced mice. Sci Rep. 2022 Nov 15;12(1):19609.|[6]Hu S, et al. Lentinan alleviates diabetic cardiomyopathy by suppressing CAV1/SDHA-regulated mitochondrial dysfunction. Biomed Pharmacother. 2023 Nov;167:115645.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Launched