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Bis-Tos-(2-hydroxyethyl disulfide)

CAT:
804-HY-140126-02
Size:
500 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Bis-Tos-(2-hydroxyethyl disulfide) - image 1

Bis-Tos-(2-hydroxyethyl disulfide)

  • CAS Number: 69981-39-1
  • UNSPSC Description: Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
  • Target Antigen: ADC Linker
  • Type: ADC Related
  • Related Pathways: Antibody-drug Conjugate/ADC Related
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/bis-tos-2-hydroxyethyl-disulfide.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=S(C1=CC=C(C)C=C1)(OCCSSCCOS(C2=CC=C(C)C=C2)(=O)=O)=O
  • Molecular Weight: 462.62
  • References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
  • Shipping Conditions: Blue Ice
  • Clinical Information: No Development Reported