Anti-AGPS Purified Monoclonal Antibody

Anti-AGPS Purified Monoclonal Antibody

• Background: AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
• Description: Boster Bio Anti-AGPS Purified Monoclonal Antibody (Catalog# M03481). Tested in Flow Cytometry, WB application(s). This antibody reacts with Human.
• Synonyms: ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY
• CAS Number: 9007-83-4
• Gene Name: AGPS
• UniProt: O00116
• Host: Mouse
• Reactivity: Human
• Immunogen: Recombinant human AGPS (amino acids 158-384). The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.
• Clonality: Monoclonal
• Applications: Flow Cytometry, WB
• Purification: Purified by protein-A affinity chromatography.
• Concentration: 1 mg/ml
• Form: Liquid
• Molecular Weight: 72912 MW
• Components: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage Conditions: Store at 2-8°C. Do not freeze.
• Fragment: Mouse IgG2a
• Clone ID: Clone: AGPS-03