Anti-ARAP1 Purified Monoclonal Antibody

Anti-ARAP1 Purified Monoclonal Antibody

• Background: ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
• Description: Boster Bio Anti-ARAP1 Purified Monoclonal Antibody (Catalog# M06167). Tested in IP, WB, ICC application(s). This antibody reacts with Human.
• Synonyms: CED2, CENTD2
• CAS Number: 9007-83-4
• Gene Name: ARAP1
• UniProt: Q96P48
• Host: Mouse
• Reactivity: Human
• Immunogen: His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1. The antibody ARAP1-2 reacts with C-terminal part of ARAP1 (intracellular epitope), a 160 kDa adaptor protein.
• Clonality: Monoclonal
• Applications: IP, WB, ICC
• Purification: Purified by protein-A affinity chromatography.
• Concentration: 1 mg/ml
• Form: Liquid
• Molecular Weight: 162192 MW
• Components: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage Conditions: Store at 2-8°C. Do not freeze.
• Fragment: Mouse IgG1
• Clone ID: Clone: ARAP1-2