Anti-Bov CD62L Purified SELL Monoclonal Antibody

Anti-Bov CD62L Purified SELL Monoclonal Antibody

• Background: CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
• Description: Boster Bio Anti-Bov CD62L Purified SELL Monoclonal Antibody (Catalog# M00652). Tested in Flow Cytometry, IP, ICC application(s). This antibody reacts with Cow, Human.
• Synonyms: L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR
• CAS Number: 9007-83-4
• Gene Name: SELL
• UniProt: P98131
• Host: Mouse
• Reactivity: Cow, Human
• Immunogen: Bovine leukocytes. The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
• Clonality: Monoclonal
• Applications: Flow Cytometry, IP, ICC
• Purification: Purified by protein-A affinity chromatography.
• Concentration: 1 mg/ml
• Form: Liquid
• Components: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage Conditions: Store at 2-8°C. Do not freeze.
• Fragment: Mouse IgG1
• Clone ID: Clone: IVA94