Anti-DPAGT1 Antibody
CAT:
519-A08142
Size:
0.1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-DPAGT1 Antibody
- Background: The UDP-N-acetylglucosamine-dolichyl-phosphate N-acetyl-glucosaminephosphotransferase (DPAGT1) is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.
- Description: Boster Bio Anti-DPAGT1 Antibody (Catalog # A08142). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
- Synonyms: GPT, ALG7, DGPT, G1PT, UAGT, UGAT, CDG1J, DPAGT, CDG-Ij, CMSTA2, DPAGT2, D11S366, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase
- CAS Number: 9007-83-4
- Gene Name: DPAGT1
- UniProt: Q9H3H5
- Host: Rabbit
- Reactivity: Human, Mouse
- Cross Reactivity: At least four isoforms of DPAGT1 are known to exist; this antibody will recognize the two longest isoforms. DPAGT1 antibody is predicted to not cross-react with UHRF1BP1.
- Immunogen: DPAGT1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human DPAGT1. The immunogen is located within amino acids 30 - 80 of DPAGT1.
- Clonality: Polyclonal
- Applications: ELISA, WB, IHC-P, IF
- Purification: DPAGT1 Antibody is affinity chromatography purified via peptide column.
- Concentration: 1 mg/mL
- Form: Liquid
- Molecular Weight: 46090 MW
- Components: DPAGT1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage Conditions: DPAGT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Fragment: IgG