Anti-Cathelicidin CAMP Antibody

Anti-Cathelicidin CAMP Antibody

• Background: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
• Description: Boster Bio Anti-Cathelicidin CAMP Antibody (Catalog # A05475). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
• Synonyms: LL37, CAP18, CRAMP, HSD26, CAP-18, FALL39, FALL-39, Cathelicidin antimicrobial peptide, 18 kDa cationic antimicrobial protein
• CAS Number: 9007-83-4
• Gene Name: CAMP
• UniProt: P49913
• Host: Rabbit
• Reactivity: Human
• Immunogen: Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the center of the human Cathelicidin. The immunogen is located within amino acids 50 - 100 of Cathelicidin.
• Clonality: Polyclonal
• Applications: ELISA, WB, IHC-P, IF
• Purification: Cathelicidin Antibody is affinity chromatography purified via peptide column.
• Concentration: 1 mg/mL
• Form: Liquid
• Molecular Weight: 19301 MW
• Components: Cathelicidin Antibody is supplied in PBS containing 0.02% sodium azide.
• Storage Conditions: Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
• Fragment: IgG