Anti-PAK6 Antibody

Anti-PAK6 Antibody

• Background: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.
• Description: Boster Bio Anti-PAK6 Antibody (Catalog # A04903). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
• Synonyms: PAK5, PAK5, PAK-5, PAK-6
• CAS Number: 9007-83-4
• Gene Name: PAK6
• UniProt: Q9NQU5
• Host: Rabbit
• Reactivity: Human
• Cross Reactivity: PAK6 antibody is predicted to not cross-react with other PAK family proteins.
• Immunogen: PAK6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human PAK6. The immunogen is located within amino acids 260 - 310 of PAK6.
• Clonality: Polyclonal
• Applications: ELISA, WB, ICC, IF
• Purification: PAK6 Antibody is affinity chromatography purified via peptide column.
• Concentration: 1 mg/mL
• Form: Liquid
• Molecular Weight: 74869 MW
• Components: PAK6 Antibody is supplied in PBS containing 0.02% sodium azide.
• Storage Conditions: PAK6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Fragment: IgG