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Recombinant Rabbit TNF-alpha/TNFSF2/TNFa Protein

CAT:
763-PKSQ050066-02
Size:
10 µg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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Recombinant Rabbit TNF-alpha/TNFSF2/TNFa Protein

  • Background: Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
  • Abbreviation: TNF-alpha;TNFSF2;TNFa
  • Synonyms: Cachectin, TNF, TNF-Alpha, TNF-a, TNFA, TNFSF2, Tumor Necrosis Factor, Tumor Necrosis Factor Ligand Superfamily Member 2
  • CAS Number: 9000-83-3
  • UniProt: P04924
  • Accession Number: P04924
  • Host: E. coli
  • Origin Species: Rabbit
  • Tag: None
  • Sequence: Val78-Leu235
  • Applications: Cell culture
  • Purity: > 95 % as determined by reducing SDS-PAGE.
  • Bioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 3. 5 pg/ml.
  • Reconstitution: Please refer to the printed manual for detailed information.
  • Molecular Weight: 18 kDa
  • Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
  • Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

MSDS