Recombinant Mouse M-CSF protein(His Tag)

Recombinant Mouse M-CSF protein(His Tag)

• Background: Macrophage colony-stimulating factor 1（M-csf）is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
• Abbreviation: M-CSF
• Synonyms: Ath, Ath-, Ath-1, Ath1, CD134, CD134L, OX-40L, OX4, TNFSF4, TXGP1, Tnlg2b, Txgp, Txgp1l, gp3, gp34
• CAS Number: 9000-83-3
• UniProt: P07141
• Accession Number: P07141
• Host: E. coli
• Origin Species: Mouse
• Tag: C-His
• Sequence: Lys32-Pro187
• Applications: Cell culture
• Purity: > 98 % as determined by reducing SDS-PAGE.
• Bioactivity: Measure by its ability to induce proliferation in NFS-60 cells.The ED₅₀ for this effect is <2 ng/mL.The specific activity of recombinant mouse M-CSF is approximately >5 x 10⁵ IU/mg.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 17-25 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.