Recombinant Mouse bFGF/FGF2 Protein (His Tag)

Recombinant Mouse bFGF/FGF2 Protein (His Tag)

• Background: Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies. bFGF/FGF2 Protein & Antibody Products
• Abbreviation: bFGF;FGF2
• Synonyms: Fgf-2, Fgfb, bFGF
• CAS Number: 9000-83-3
• UniProt: P15655
• Accession Number: P15655
• Host: E. coli
• Origin Species: Mouse
• Tag: N-His
• Sequence: Ala11-Ser154
• Applications: Cell culture
• Purity: > 98 % as determined by reducing SDS-PAGE.
• Bioactivity: Measure by its ability to induce 3T3 cells proliferation. The ED₅₀ for this effect is <1.5 ng/mL. The specific activity of recombinant mouse FGF-2 is approximately >1 x 10⁶ IU/mg.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 19 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.