Recombinant Human β-NGF/NGFB Protein (with pro peptide)
CAT:
763-PKSH033552-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human β-NGF/NGFB Protein (with pro peptide)
- Background: The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges; whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
- Abbreviation: β-NGF;NGFB
- Synonyms: Beta-NGF, Beta-Nerve Growth Factor, NGF, NGFB
- CAS Number: 9000-83-3
- UniProt: P01138
- Accession Number: P01138
- Host: E. coli
- Origin Species: Human
- Tag: None
- Sequence: Glu19-Ala241
- Field of Research: Neuroscience
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 30 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.