Cyclo(L-Leu-L-Pro)

Cyclo(L-Leu-L-Pro)

• CAS Number: 2873-36-1
• UNSPSC Description: Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4[1].
• Target Antigen: Fungal
• Type: Peptides
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/cyclo-l-leu-l-pro.html
• Purity: 99.84
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: O=C(N1[C@]([H])2CCC1)[C@@H](NC2=O)CC(C)C
• Molecular Weight: 210.27
• References & Citations: [1]Yan PS, et al. Cyclo(L-leucyl-L-prolyl) produced by Achromobacter xylosoxidans inhibits aflatoxin production by Aspergillus parasiticus. Appl Environ Microbiol. 2004 Dec;70(12):7466-73.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported