MC-DM1

CAT:

804-HY-136286-01

Size:

1 mg

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CAS Number: 1375089-56-7
UNSPSC Description: MC-DM1 is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody agent conjugate (ADC)[1].
Target Antigen: Drug-Linker Conjugates for ADC
Type: ADC Related
Related Pathways: Antibody-drug Conjugate/ADC Related
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/mc-dm1.html
Smiles: C[C@]1([C@H](CC(N(C(C=C(C2)C=C3OC)=C3Cl)C)=O)OC([C@H](C)N(C)C(CCCCCN(C4=O)C(C=C4)=O)=O)=O)[C@@]([C@@H]([C@](OC5=O)([H])C[C@]([C@@H](/C=C/C=C2\C)OC)(N5)O)C)([H])O1
Molecular Weight: 843.36
References & Citations: [1]Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.
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