Eribulin-d3 (mesylate)

CAT:

804-HY-13442AS-01

Size:

500 µg

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UNSPSC Description: Eribulin-d3 (mesylate) is a deuterium labeled Eribulin mesylate. Eribulin mesylate is a microtubule targeting agent that is used for the research of cancer[1][2].
Target Antigen: Apoptosis; Microtubule/Tubulin
Type: Isotope-Labeled Compounds
Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Field of Research: Cancer
Smiles: C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](O)CN)[C@@H]9OC([2H])([2H])[2H])([H])[C@]9([H])CC5=O.CS(=O)(O)=O
Molecular Weight: 829.02
References & Citations: [1]Russak EM, et, al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Watanabe K, et, al. Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo. Oncotarget. 2019 Jan 4;10(2):161-174.
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