N-Methyl-DL-valine (hydrochloride)
CAT:
804-HY-W142140A-02
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
N-Methyl-DL-valine (hydrochloride)
- UNSPSC Description: N-Methyl-DL-valine (N-Methylvaline) hydrochloride is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine hydrochloride involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/n-methyl-dl-valine-hydrochloride.html
- Purity: 98.0
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C(C(C(C)C)NC)O.[H]Cl
- Molecular Weight: 167.63
- References & Citations: [1]M. Pasteels, et al. Uptake and metabolism of [14C]rinderine and [14C]retronecine in leaf-beetles of the genus Platyphora and alkaloid accumulation in the exocrine defensive secretions. Chemoecology. 2003;13:55–62.|[2]Philip N Moquist, et al. Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux–positive Tumor Models. Mol Cancer Ther.2021;20(2): 320–328.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported