Azithromycin

Azithromycin

• CAS Number: 83905-01-5
• UNSPSC Description: Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
• Target Antigen: Antibiotic; Autophagy; Bacterial; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Autophagy
• Applications: COVID-19-anti-virus
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/Azithromycin.html
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: C[C@@H]([C@@H]([C@@](C(O[C@@H]([C@@](C)(O)[C@@H]1O)CC)=O)([H])C)O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@@]2(C)OC)[C@H]([C@](O)(C[C@H](CN([C@@H]1C)C)C)C)O[C@@](O[C@H](C)C[C@@H]3N(C)C)([H])[C@@H]3O
• Molecular Weight: 748.98
• References & Citations: [1]Menzel M, et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. Oncotarget. 2017 Mar 18.|[2]Vandooren J, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. PLoS One. 2017 Apr 3;12(4):e0174853.ACS Chem Biol. 2021 Dec 15.|ACS Infect Dis. 2024 Apr 12;10(4):1327-1338.|ACS Omega. March 3, 2022.|Acta Pharm Sin B. 2021 Mar 11.|Adv Sci (Weinh). 2020 Jul 21;7(17):2001374.|Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Biochem Pharmacol. 2021 Sep 30;114793.|bioRxiv. 2021 Jan 19.|bioRxiv. 2024 Apr 4.|bioRxiv. 2024 May 10.|Cell Rep. 2023 Dec 12;42(12):113563.|COVID. 2021, 1(1), 263-275.|Emerg Microbes Infect. 2024 Dec;13(1):2321981.|Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. 2020 Sep.|Invest Ophthalmol Vis Sci. 2021 Feb 1;62(2):33.|iScience. 5 January 2022, 103731.|Journal of Pharmaceutical Research International. 33(47B): 274-279, 2021.|Katedra farmakologie a toxikologie. 2020 Jul.|Patent. US20200101105A1.|Research Square Preprint. 2022 Jun.|Theranostics. 2022 Jan 1;12(3):1187-1203.|Viruses. 2019 Nov 15;11(11):1064.|Viruses. 2020 Jun 10;12(6):628.|Mol Ther. 2022 Feb 18;S1525-0016(22)00102-2.
• Shipping Conditions: Room Temperature
• Clinical Information: Launched