Acyclovir
CAT:
804-HY-17422-04
Size:
500 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Acyclovir
- CAS Number: 59277-89-3
- UNSPSC Description: Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[1][2][3][4].
- Target Antigen: Antibiotic; Apoptosis; Bacterial; HSV
- Type: Reference compound
- Related Pathways: Anti-infection;Apoptosis
- Applications: COVID-19-anti-virus
- Field of Research: Cancer; Infection
- Assay Protocol: https://www.medchemexpress.com/Acyclovir.html
- Solubility: DMSO : ≥ 50 mg/mL
- Smiles: O=C1NC(N)=NC2=C1N=CN2COCCO
- Molecular Weight: 225.208
- References & Citations: [1]Benedetti S, et, al. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells, and enhances chemotherapeutic drug cytotoxicity. Life Sci. 2018 Dec 15;215:80-85.|[2]Suzuki M, et, al. Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Antiviral Res. 2006 Nov;72(2):157-61.|[3]Li Z, et, al. Acyclovir treatment of skin lesions results in immune deviation in mice infected cutaneously with herpes simplex virus. Antivir Chem Chemother. 1999 Sep;10(5):251-7.|[4]Lönnqvist B, et, al. Oral acyclovir as prophylaxis for bacterial infections during induction therapy for acute leukaemia in adults. The Leukemia Group of Middle Sweden. Support Care Cancer. 1993 May;1(3):139-44.
- Shipping Conditions: Room Temperature
- Clinical Information: Launched