MNI-caged-NMDA

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804-HY-107717

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CAS Number: 1227675-52-6
UNSPSC Description: MNI-caged-NMDA is a light-sensitive amino acid with rapid release properties suitable for use in the study of fast synaptic receptor mechanisms. MNI-caged-NMDA shows metered release of NMDA receptors, inducing rapid and sustained receptor activation in cerebellar interneurons. MNI-caged-NMDA is able to achieve rapid transient responses and generate large inward currents by local laser photolysis. The use of MNI-caged-NMDA can effectively study neurotransmitter signaling and its inhibitory effects on GABA-A receptors[1].
Target Antigen: iGluR
Type: Reference compound
Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
Applications: Neuroscience-Neuromodulation
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/mni-caged-nmda.html
Smiles: O=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O
Molecular Weight: 323.30
References & Citations: [1]New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups
Shipping Conditions: Room temperature
Clinical Information: No Development Reported