MNI-caged-NMDA

MNI-caged-NMDA

• CAS Number: 1227675-52-6
• UNSPSC Description: MNI-caged-NMDA is a light-sensitive amino acid with rapid release properties suitable for use in the study of fast synaptic receptor mechanisms. MNI-caged-NMDA shows metered release of NMDA receptors, inducing rapid and sustained receptor activation in cerebellar interneurons. MNI-caged-NMDA is able to achieve rapid transient responses and generate large inward currents by local laser photolysis. The use of MNI-caged-NMDA can effectively study neurotransmitter signaling and its inhibitory effects on GABA-A receptors[1].
• Target Antigen: iGluR
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/mni-caged-nmda.html
• Smiles: O=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O
• Molecular Weight: 323.30
• References & Citations: [1]New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported