TGF-alpha Recombinant Protein
CAT:
209-100-103S
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TGF-alpha Recombinant Protein
- Description: TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
- Synonyms: TGFA; TFGA
- CAS Number: 9000-83-3
- NCBI Gene ID: 7039
- UniProt: P01135
- Accession Number: NP_003227.1
- Accession Number mRNA: NM_003236
- Gene Location: 2p13
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Chicken, Mouse, Rat, Human, Horse
- Sequence: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
- Detection Range: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 50
- Form: Lyophilized
- Molecular Weight: 5.5 kDa
- Shipping Conditions: Room Temperature