IGF-BP2 Recombinant Protein
CAT:
209-100-198S
Size:
5 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IGF-BP2 Recombinant Protein
- Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.
- Synonyms: IGFBP2; IBP2; IGF-BP53
- CAS Number: 9000-83-3
- NCBI Gene ID: 3485
- UniProt: P18065
- Accession Number: NP_000588.2
- Accession Number mRNA: NM_000597
- Gene Location: 2q33-q34
- Host: Insect Cells
- Origin Species: Human
- Species Reactivity: Mouse
- Sequence: EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
- Detection Range: Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 289
- Form: Lyophilized
- Molecular Weight: 31.5 kDa
- Shipping Conditions: Room Temperature