BMP-4 Recombinant Protein
CAT:
209-100-326H
Size:
5 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BMP-4 Recombinant Protein
- Description: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
- Synonyms: BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS7
- CAS Number: 9000-83-3
- NCBI Gene ID: 652
- UniProt: P12644
- Accession Number: NP_001193
- Accession Number mRNA: NM_001202
- Gene Location: 14q22-q23
- Host: HeLa Cells
- Origin Species: Human
- Species Reactivity: Human, Mouse, Rat
- Sequence: HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR
- Detection Range: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml.
- Purity: >97% by SDS-PAGE and HPLC anaylsis
- Length: 113
- Form: Lyophilized
- Molecular Weight: 25,6 kDa
- Shipping Conditions: Room Temperature