Rabbit Anti-Human BDNF Polyclonal Antibody
CAT:
209-102-P02
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rabbit Anti-Human BDNF Polyclonal Antibody
- Description: BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.
- Synonyms: BDNF
- CAS Number: 9007-83-4
- NCBI Gene ID: 627
- UniProt: P23560
- Accession Number: NP_733931.1
- Accession Number mRNA: NM_170735.5
- Gene Location: 11p13
- Host: Rabbit
- Origin Species: Human
- Species Reactivity: Human, Mouse, Rat
- Target Antigen: E.coli derived Recombinant Human BDNF
- Clone: Rabbit IgG
- Validated Applications: ELISA, WB, N, IHC
- Purification Method: Antigen-affinity purified
- Form: Lyophilized from PBS
- Buffer: PBS
- Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.