2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
CAT:
804-HY-154414-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
- CAS Number: 1404463-12-2
- UNSPSC Description: 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
- Target Antigen: Nucleoside Antimetabolite/Analog
- Type: Oligonucleotides
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/2-fluoro-2-deoxy-ara-c-bz-3-phosphoramidite.html
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F
- Molecular Weight: 851.90
- References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported