PPM1H Antibody
CAT:
400-SMC-616D
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No






PPM1H Antibody
- Background: PPM1H is an independent prognostic biomarker of non-small cell lung cancer (1). PPM1H acts as a key modulator of LRRK2 signaling by controlling dephosphorylation of Rab proteins (2). PPM1H is also suggested to be a gatekeeper to prevent excessive bone morphogenetic protein (BMP) signalling through dephosphorylation (3).
- Description: Human Anti-Human PPM1H Monoclonal IgG1
- Specifications: Detects ~55kDa
- Product Name Alternative: Protein phosphatase Mg2+/Mn2+ dependent 1H Antibody | NERPP2C | Protein phosphatase 1H Antibody
- Synonyms: PPM1H Antibody, Clone 10D2
- CAS Number: 9007-83-4
- UNSPSC: 12352203
- Gene ID: 57460
- Swiss Prot: Q9ULR3
- Accession Number: NP_065751.1
- Cellular Locus: Intracellular
- Host: Mouse
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Recombinant Human PPM1H Protein
- Target: PPM1H
- Clonality: Monoclonal
- Isotype: IgG1
- Clone: 10D2
- Conjugation: Unconjugated
- Tissue Specificity: Parathyroid gland
- Validated Applications: WB, ICC/IF
- Purification: Protein G Purified
- Limit Of Detection: A 1:1000 dilution of SMC-616 was sufficient for detection of PPM1H in 10 µg of Hu, Ms, Rt Kidney Cells (HEK293), Alveolar Basal Epithelial cells (A549) by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
- Concentration: 1 mg/ml
- Dilution: WB (1:1000), ICC/IF (1:500); optimal dilutions for assays should be determined by the user.
- Weight: 0.1
- Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- References & Citations: 1. Zhang W.Q., et al. (2021) Neoplasma. 68(5): 917-923. 2. Berndsen K., et al. (2019) 8:e50416. 3.Shen T., et al. (2014) Cell Res. 24(6): 727-741.