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PPM1H Antibody

CAT:
400-SMC-616D
Size:
100 µg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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PPM1H Antibody

  • Background: PPM1H is an independent prognostic biomarker of non-small cell lung cancer (1). PPM1H acts as a key modulator of LRRK2 signaling by controlling dephosphorylation of Rab proteins (2). PPM1H is also suggested to be a gatekeeper to prevent excessive bone morphogenetic protein (BMP) signalling through dephosphorylation (3).
  • Description: Human Anti-Human PPM1H Monoclonal IgG1
  • Specifications: Detects ~55kDa
  • Product Name Alternative: Protein phosphatase Mg2+/Mn2+ dependent 1H Antibody | NERPP2C | Protein phosphatase 1H Antibody
  • Synonyms: PPM1H Antibody, Clone 10D2
  • CAS Number: 9007-83-4
  • UNSPSC: 12352203
  • Gene ID: 57460
  • Swiss Prot: Q9ULR3
  • Accession Number: NP_065751.1
  • Cellular Locus: Intracellular
  • Host: Mouse
  • Species Reactivity: Human, Mouse, Rat
  • Immunogen: Recombinant Human PPM1H Protein
  • Target: PPM1H
  • Clonality: Monoclonal
  • Isotype: IgG1
  • Clone: 10D2
  • Conjugation: Unconjugated
  • Tissue Specificity: Parathyroid gland
  • Validated Applications: WB, ICC/IF
  • Purification: Protein G Purified
  • Limit Of Detection: A 1:1000 dilution of SMC-616 was sufficient for detection of PPM1H in 10 µg of Hu, Ms, Rt Kidney Cells (HEK293), Alveolar Basal Epithelial cells (A549) by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
  • Concentration: 1 mg/ml
  • Dilution: WB (1:1000), ICC/IF (1:500); optimal dilutions for assays should be determined by the user.
  • Weight: 0.1
  • Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated
  • Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
  • References & Citations: 1. Zhang W.Q., et al. (2021) Neoplasma. 68(5): 917-923. 2. Berndsen K., et al. (2019) 8:e50416. 3.Shen T., et al. (2014) Cell Res. 24(6): 727-741.

Datasheet

MSDS