BMS-986115
CAT:
804-HY-12860-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BMS-986115
- Product Name Alternative: Notch inhibitor 1
- CAS Number: 1584647-27-7
- UNSPSC Description: BMS-986115 (Notch inhibitor 1) is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].
- Target Antigen: Notch
- Type: Reference compound
- Related Pathways: Neuronal Signaling;Stem Cell/Wnt
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bms-986115.html
- Purity: 99.90
- Solubility: DMSO : 13.12 mg/mL (ultrasonic;warming;heat to 70°C)
- Smiles: O=C(N[C@@H]1C(NC2=C(C)C=CC=C2C(C3=CC=CC(F)=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O
- Molecular Weight: 574.49
- References & Citations: [1]Ashvinikumar V. Gavai, et al. Bis(fluoroalkyl)-1,4-benzodiazepinone compounds as notch inhibitors. WO2014047372A1.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, stored under nitrogen)
- Clinical Information: Phase 1