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Human CellExp™ TNF-alpha Extracellular Domain, Human Recombinant

CAT:
26-P1392-10
Size:
10 µg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Human CellExp™ TNF-alpha Extracellular Domain, Human Recombinant - image 1

Human CellExp™ TNF-alpha Extracellular Domain, Human Recombinant

  • Description: Tumor Necrosis Factor-α (TNF-α) is a highly pleiotropic cytokine with multiple activities other than its originally discovered role of tumor necrosis in rodents. It contributes to both inflammations during infections and anti-inflammatory/tissue repair processes after clearance of infection. TNF-α is mainly produced by activated macrophages, T lymphocytes, and natural killer (NK) cells. The activity of TNF-α is mediated through two cell surface receptors, TNF-R1 (p55) and TNF-R2 (p75) that differ in their signaling activity. TNF-α's primary role is in the regulation of immune cells. It can induce cell death of certain tumor cell lines. About 28% of cancers are susceptible to direct cell killing mediated by soluble TNF-α.
  • CAS Number: 9000-83-3
  • Shipping Conditions: Gel Pack
  • Storage Conditions: -20°C
  • Shelf Life: 12 months