Human CellExp™ PD-L2 / B7-DC, mouse recombinant

Human CellExp™ PD-L2 / B7-DC, mouse recombinant

• Description: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
• CAS Number: 9000-83-3
• Shipping Conditions: Gel Pack
• Storage Conditions: -20°C
• Shelf Life: 12 months