GPX4-IN-10

• UNSPSC Description:

  GPX4-IN-10 (compound I20) is a non-covalent GPX4 inhibitor. GPX4-IN-10 induces ferroptosis and inhibits cell growth of HT1080 cells[1].

• Target Antigen:

  Ferroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gpx4-in-10.html

• Smiles:

  CC1CCN(CC2=CC=C(NC(CN3C(C)=C(C(N(C4=CC=CC=C4)N=C5)=O)C5=C3C)=O)C=C2)CC1

• Molecular Weight:

  483.60

• References & Citations:

  [1]Huang W, et al. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Eur J Med Chem. 2024 Jul 10;276:116670.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported