CDK8-IN-3

• CAS Number:

  1884500-15-5

• UNSPSC Description:

  CDK8-IN-3 is an inhibitor of CDK8 extracted from patent WO2016041618A1, compound example 1.7.

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/CDK8-IN-3.html

• Purity:

  99.21

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(NCCOC)C1=CC=C2C(C(CC3=CC=C(C4=CN(C)N=C4)C=C3)=NN2)=C1

• Molecular Weight:

  389.45

• References & Citations:

  [1]Kai S, et al. Preparation of substituted indazoles as CDK8 inhibitors for treatment of proliferative diseases. WO 2016041618 A1 20160324

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported