Rap1B ΔC Ras-proximate 1B, deletion of 17 C-terminal residues human, recombinant, E. coli

• Description:

  Rap (Ras-proximate) proteins are GTPases that belong to the Ras superfamily of small GTP binding proteins. Rap1B is known to antagonize the mitotic and transforming activity of Ras. Rap1B can be activated by cAMP known to either stimulate or inhibit cell proliferation. The deletion of 17 C-terminal amino acids in Rap1B ΔC leads to the loss of the phosphorylation site Ser179 and the geranyl-geranylation site. Protein preparation is 53% GDP- and 47% GTP-loaded, measured by HPLC.

• CAS Number:

  9000-83-3

• UNSPSC:

  12352202

• UNSPSC Description:

  Proteins

• HS Code:

  35079090

• Accession Number:

  NM_015646

• eClass Number:

  34160400

• eClass Product Group:

  Peptide and Protein

• Purity:

  > 90 % (SDS-PAGE)

• Form:

  Liquid (Supplied in 64 mM Tris-HCl pH 7.0, 5 mM DTE, 400 mM NaCl, 10 mM MgCl2 and 0.1 mM GDP)

• Autoclavability:

  false

• Shipping Conditions:

  Shipped on dry ice.

• Storage Conditions:

  Store at -80 °C. Avoid freeze/thaw cycles.

• Shelf Life:

  12 months