Anti-TNF-alpha

Anti-TNF-alpha

• Description: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
• CAS Number: 9007-83-4
• Reactivity: Human
• Immunogen: Recombinant protein
• Clonality: Polyclonal
• Type: Antibodies-Polyclonal
• Applications: WB
• Concentration: 100ug/100ul
• Purity: Affinity purified
• Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
• Shipping Conditions: Ice Pack
• Storage Conditions: This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
• Fragment: IgG
• Specificity: Human
• Applications Notes: Optimal dilutions to be determined by researchers