Maleimide

Maleimide

• CAS Number: 541-59-3
• UNSPSC Description: Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].
• Target Antigen: ADC Linker
• Type: Natural Products
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/maleimide.html
• Purity: 99.98
• Solubility: DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
• Smiles: O=C(N1)C=CC1=O
• Molecular Weight: 97.07
• References & Citations: [1]Renault K, et, al. Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies. Bioconjug Chem. 2018 Aug 15;29(8):2497-2513.|[2]Zhang S, et, al. A Maleimide-functionalized Tetraphenylethene for Measuring and Imaging Unfolded Proteins in Cells. Chem Asian J. 2019 Mar 15;14(6):904-909.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported