9-Hydroxyoctadecanoic acid
CAT:
804-HY-N11692-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
9-Hydroxyoctadecanoic acid
- CAS Number: 3384-24-5
- UNSPSC Description: 9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity[1].
- Target Antigen: HDAC
- Type: Natural Products
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/9-hydroxyoctadecanoic-acid.html
- Purity: 98.0
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C(CCCCCCCC(CCCCCCCCC)O)O
- Molecular Weight: 300.48
- References & Citations: [1]Calonghi N, et al. Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer. J Lipid Res. 2005 Aug;46(8):1596-603.|[2]Calonghi N, et al. 9-Hydroxystearic acid upregulates p21(WAF1) in HT29 cancer cells. Biochem Biophys Res Commun. 2004 Jan 30;314(1):138-42.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported