Bodipy C12-ceramide

Bodipy C12-ceramide

• CAS Number: 1246355-58-7
• UNSPSC Description: Bodipy C12-ceramide (B12Cer) is a fluorescently tagged form of C12-Ceramide (HY-100353) that displays excitation/emission maxima of 505/540 nm, respectively. Bodipy C12-ceramide is formed when acid sphingomyelinase hydrolyzes BODIPY-C12 sphingomyelin in vitro and has been used to quantify acid sphingomyelinase activity in plasma with Niemann-Pick disease[1].
• Target Antigen: Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/bodipy-c12-ceramide.html
• Smiles: CC1=CC(C)=[N+]2C1=C(CCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO)=O)C3=C(C)C=C(C)N3[B-]2(F)F
• Molecular Weight: 713.83
• References & Citations: [1]He X, et al. A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick disease. Anal Biochem. 2003 Mar 1;314(1):116-20.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported