Argatroban-13C6 (hydrochloride)

Argatroban-13C6 (hydrochloride)

• UNSPSC Description: Argatroban-13C6 hydrochloride is 13C labeled Argatroban (HY-B0375). Argatroban (MD-805) is a direct, selective thrombin inhibitor.
• Target Antigen: Isotope-Labeled Compounds; Thrombin
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/argatroban-13c6-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@@H]1N(C([C@@H](NS(=O)([13C]2=[13CH][13CH]=[13CH][13C]3=[13C]2NCC(C)C3)=O)CCCNC(N)=N)=O)CC[C@@H](C)C1)O.Cl
• Molecular Weight: 551.05
• References & Citations: [1]Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9.|[2]Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported