ADC Control Human IgG1-vcMMAE

• UNSPSC Description:

  ADC Control Human IgG1-vcMMAE is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is vcMMAE (HY-15575)[1].

• Target Antigen:

  Antibody-Drug Conjugates (ADCs); Microtubule/Tubulin

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/adc-control-human-igg1-vcmmae.html

• Smiles:

  [ADC Control Human IgG1-vcMMAE]

• References & Citations:

  [1]Tushar D Nichakawade, et al. TRBC1-targeting antibody-drug conjugates for the treatment of T cell cancers. Nature. 2024 Apr;628(8007):416-423.

• Shipping Conditions:

  Dry Ice

• Clinical Information:

  No Development Reported