Folic acid (disodium)

Folic acid (disodium)

• CAS Number: 29704-76-5
• UNSPSC Description: Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·105 g/s[1]. Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia[2].
• Target Antigen: DNA/RNA Synthesis; Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Neurological Disease; Others
• Assay Protocol: https://www.medchemexpress.com/folic-acid-disodium.html
• Solubility: H2O : ≥ 100 mg/mL
• Smiles: O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(NCC2=CN=C3N=C(N)NC(C3=N2)=O)C=C1)=O
• Molecular Weight: 485.36
• References & Citations: [1]Braga D., et al., Folic Acid in the Solid State: A Synergistic Computational, Spectroscopic, and Structural Approach, Crystal Growth & Design, 2016, 16, 4, 2218–222.|[2]Shulpekova Y, et al., The Concept of Folic Acid in Health and Disease. Molecules. 2021 Jun 18;26(12):3731.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported